Celiac Plexus is a group of nerves that supplies organs into the abdomen. A Celiac Plexus Block/Neurolysis may be performed if the patient is experiencing severe chronic abdominal pain commonly due to cancer or chronic pancreatitis. The doctor starts by placing an intravenous (IV) catheter in your arm and gives you a dose of IV fluid before the procedure. The patient lies on the stomach and the back is cleaned with an antiseptic and numbed with medication. Under the guidance of an X-ray or CT scan, needles are inserted through the skin and local anesthetic is injected to block the celiac plexus.